If you're unhappy at your current club, or thinking of moving on, you can start a thread in Jobs and get your feelings noticed. Also, if a club has become unmanaged which you would like to move to you can do the same. This section is a place where managers can voice their career plans.
Important - loyalty. By expressing an interest in another club you will lose some of the support of your board and fans. Keeping the fans and chairman happy will make staying at the current club easier, so showing a lack of loyalty could make your situation more difficult.
Important - timescale. Jobs are handed out in a realistic manner. If you've only been in the game 5 minutes you won't be allowed to leave your current club. Generally managers are expected to spend about a season at a club before they consider leaving.
Important - careers. Jobs are handed out in a realistic manner. If you are manager of an underachieving League One club, you are likely to be rejected if you try to apply for a top Premiership clubs position. Consider this before applying as you could needlessly lose chairman and fan support by applying for an unrealistic job where you get rejected straight away.
Your career is in your hands, so your decisions will have consequences on your reputation.